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Do you have cardiovascular disease and elevated cholesterol levels?
See if you qualify to participate in the PREVAIL study
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PREVAIL is clinical research study evaluating the safety and effectiveness of an investigational drug in people who have cardiovascular disease. The study drug is designed to lower cholestrol specifically low-density lipo-protien cholestrol(LDL-C), known as the harmful or "bad" form of cholestrol.
Study Overview
Have study clinic and telephone visits for about 3 to 4 years.
Take one tablet of either the study drug or a placebo(no active ingredients) by mouth once daily.
Continue taking your medication to lower cholestrol that was prescribed by your general practitioner(if applicable).
Follow a cholestrol-lowering diet and make lifestyle changes as instructed you general practitioner
Have 1 follow-up visit after your last dose of the assigned study drug or placebo(via telephone).
Key study requirements
You have a history of cardiovascular disease.
You are 18 years of age or older and have elevated bad "cholestrol" levels:
Fasting LDL-C of 100 mg/dL (2.6 mmol/L) OR greater.
OR
Fasting LDL-C of 55 mg/dL (1.4 mmol/L) to 100 mg/dL (2.6 mmol/L) with at least 1 of the following risk factors:
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Recent heart attack (about 3 months ago to less than 1 year).
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Type 2 diabetes;
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Other blood test results such as fasting triglycerides greater than 150 mg/dL(1.7 mmol/L), or fasting HDL-C less than 40 mg/dL(1.0 mmol/L)(the "good" form of cholesterol).
You are taking medication(s) to lower cholesterol(if applicable) such as statin(s).
You may be eligible if you are taking a low dose of statin medication or a combination of cholesterol-lowering medications